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Jaypee Institute of Information Technology, Noida
Assistant Professor (Senior Grade)
priyadarshini@jiit.ac.in
(+91)-120-2594 211

BIOGRAPHY

Priyadarshini is an Assistant Professor in the Department of Biotechnology at Jaypee Institute of Information Technology since July 2011. Prior to this she was teaching at JUIT, Waknaghat from January 2010 to June 2011. She completed her PhD from JUIT, Waknaghat, where her research focus was identification of proteins from human stone matrix involved in Urolithiasis. She pursued her M.Sc. in zoology from Ranchi University, Ranchi.

RESEARCH HIGHLIGHTS

My research focuses on understanding the molecular mechanism of urolithiasis. Since urolithiasis is a multifactorial disease, investigating the factors underlying the cause and curative management of this disease is the general goal of my research. Various biomolecules and reactive oxygen species is important factors which influence mechanism of kidney stone formation. The research work involved the identification and characterization of a novel protein inhibitor against calcium oxalate crystal growth.  Different phytocompounds have antiurolithiatic properties, we are trying to combine these phytocompounds to prepare an effective anti-urolithiatic formulation.

PUBLICATIONS

 

  • Manavi Jain, Paramveer Yadav, Priyadarshini. "Proteomics study in Urolithiasis".Current Proteomics, 2020, 17 DOI: 10.2174/1570164616666190722161823 [Scopus Indexed Impact factor: 0.757]
  • Priyadarshini, DeveshRaizada, Pragya Kumar, Tanya Singh, Trisha Pruthi, Abhishek Negi, Lokesh Nigam and Naidu Subbarao. Exploring the modulatory effect of albumin on calcium phosphate crystallization. Current Science, Vol. 117, No. 6, 25 September 2019 [Indexed in SCOPUS Impact Factor: 0.856]
  • Nancy Taneja and Priyadarshini. “Mass Spectrometric Analysis of Proteins of L6 Skeletal Muscle Cells Under Different Glucose Conditions and Vitamin D Supplementation”. Protein & Peptide Letters, 2018, 25,  [Indexed in SCOPUS Impact Factor:1.13]

 

  • D. Raizada, P. Kumar, T. Singh, T. Pruthi, Priyadarshini. "Albumin and its role in urolithiasis". Asian J Pharm Clin Res, Vol 10, Issue 10, 2017, 32-35. [Indexed in SCOPUS Impact Factor:0.49]
  • Abhishek Negi, Shahrukh Husain, Priyadarshini, “A Review on Role of miRNA in Kidney Diseases”.Journal of Global Pharma Technology. 2017; 05(9):28-36.
  • Priyadarshini, K. Jain, R. Sood. “Evaluation of renal epithelial cell protein under stress condition”. Int J Pharm Pharm Sci, Vol 8, Issue 11,2016, 337-340.
  • Priyadarshini,K. Jain. “Cytoprotective effect ofOcimumextract on injured renal epithelial cells”. Int J Pharm Pharm Sci, Vol 7, Issue 10, October 2015, 15-18.
  • K. Aggarwal, S. Tandon, P. Pathak, S. K. Singh, C. Tandon. “Identification ofNovel Antilithiatic Cationic Proteins from Human Calcium Oxalate Renal Stone Matrix by MALDI TOF MS,” European Urology Supplements, Feb 2012, Vol 11, Issue 1. [Indexed in PubMed & SCOPUS Impact Factor:3.1
  • Priyadarshini, P.K. Naik, D Sengupta., S.K. Singh, C. Tandon. “Mode of interaction of calcium oxalate crystal with human phosphate cytidylyltransferase 1: a novel inhibitor purified from human renal stone matrix”.Journal of Biomedical Science and Engineering, Vol 4. pp. 591-598, 2011.
  • Priyadarshini,S.K. Singh, C. Tandon. “Effect of biomolecules from human renal stone matrix of calcium oxalate monohydrate stones on in vitro calcium phosphate crystallization”.International Brazilian Journal of Urology,Vol. 36 Number 5, pp. 621-62, 2010. [indexed in PubMed Impact Factor 1.342]
  • Priyadarshini, S.K. Singh, C. Tandon. “Mass spectrometric identification of human phosphate cytidyltransferse 1 as a novel calcium oxalate crystal growth inhibitor purified from human renal stone matrix”.ClinicaChimica Acta,Vol.408 pp. 34-38, 2009. [Indexed in PubMed & SCOPUS Impact Factor: 2.69]
  • Patent filed: Synergistic effect of herbal plant extract against urolithiasis.  Ref.no./application no. 202011019986. App. Number temp/e- 1/21836/2020-DEL

PUBLICATION/PRESENTATION IN NATIONAL/ INTERNATIONAL CONFERENCES

  • Shivani Sharma, Priyadarshini. "Diabetic nephropathy and phytocompounds as their therapeutic agents" in International Conference on Advances in Biosciences and Biotechnology - ICABB-2019 (January 31-February 02, 2019) Organized by Department of Biotechnology, Jaypee Institute of Information Technology, Noida.
  • Aishwarya Tyagi, Rifa Khan, Vrinda Sharma, Priyadarshini. "Comparative study of selected indian medicinal plants “in International Conference on Advances in Biosciences and Biotechnology - ICABB-2019 (January 31-February 02, 2019) Organized by Department of Biotechnology, Jaypee Institute of Information Technology, Noida.
  • Paramveer Yadav, Priyadarshini. "Protein network analysis in urolithiasis" in International Conference on Advances in Biosciences and Biotechnology - ICABB-2019 (January 31-February 02, 2019) Organized by Department of Biotechnology, Jaypee Institute of Information Technology, Noida.
  • Manavi Jain, Priyadarshini. "Proteomic analysis of renal stone matrix" in International Conference on Advances in Biosciences and Biotechnology - ICABB-2019 (January 31-February 02, 2019) Organized by Department of Biotechnology, Jaypee Institute of Information Technology, Noida
  • Chetna Faujdar, Priyadarshini. "Role of hyperoxaluria and calcium oxalate crystals in urolithiasis" in International Conference on Advances in Biosciences and Biotechnology - ICABB-2019 (January 31-February 02, 2019) Organized by Department of Biotechnology, Jaypee Institute of Information Technology, Noida
  • Aishwarya Tyagi, Rifa Khan, Priyadarshini. "Agrobiotechnology in modern era" in International Conference on Advances in Biosciences and Biotechnology - ICABB-2019 (January 31-February 02, 2019) Organized by Department of Biotechnology, Jaypee Institute of Information Technology, Noida.
  • Rifa Khan, Aishwarya Tyagi, Priyadarshini. "Bioremediation of plastic waste" in International Conference on Advances in Biosciences and Biotechnology - ICABB-2019 (January 31-February 02, 2019) Organized by Department of Biotechnology, Jaypee Institute of Information Technology, Noida
  • Shikha Mishra, Shivani Sharma, Priyadarshini. "Biological pathways and diseases" in International Conference on Advances in Biosciences and Biotechnology - ICABB-2019 (January 31-February 02, 2019) Organized by Department of Biotechnology, Jaypee Institute of Information Technology, Noida.
  • Sidhi Mishra, Simrat Kaur, Utsav Bhardwaj, Priyadarshini."Current cancer vaccines" in International Conference on Advances in Biosciences and Biotechnology - ICABB-2018 (February 01-03, 2018) Organized by Department of Biotechnology, Jaypee Institute of Information Technology, Noida.
  • Fpratishthika Singh, Priyadarshini."Effect of Inhibitors and stimulators in Nephrolithiasis" in International Conference on Advances in Biosciences and Biotechnology - ICABB-2018 (February 01-03, 2018) Organized by Department of Biotechnology, Jaypee Institute of Information Technology, Noida.
  • Nancy Taneja, Priyadarshini."Analysis of L6 skeletal muscle cells proteins expressed on exposure to diverse glucose concentration using MALDI-TOF" in International Conference on Advances in Biosciences and Biotechnology - ICABB-2018 (February 01-03, 2018) Organized by Department of Biotechnology, Jaypee Institute of Information Technology, Noida.
  • Lavina Rajput, Aditi Agarwal, Vipin Verma, Priyadarshini."Evaluation of boswellic acid derived from Boswellia serrata as anti-inflammatory and anti-oxidant agent" in International Conference on Advances in Biosciences and Biotechnology - ICABB-2018 (February 01-03, 2018) Organized by Department of Biotechnology, Jaypee Institute of Information Technology, Noida.
  • Chetna Faujdar, Priyadarshini."Phytptherapy: Emerging Trend for ROS Induced Urolithiasis" in International Conference on Advances in Biosciences and Biotechnology - ICABB-2018  (February 01-03, 2018) Organized by Department of Biotechnology, Jaypee Institute of Information Technology, Noida.
  • Akanksha Krishnan, Priyadarshini."Antiurolithiatic Properties of Bryophyllum pinnatum" in International Conference on Advances in Biosciences and Biotechnology - ICABB-2018  (February 01-03, 2018) Organized by Department of Biotechnology, Jaypee Institute of Information Technology, Noida.
  • Bhavya Lamba, Priyadarshini."Macrotyloma uniflorum and it's medicinal properties" in International Conference on Advances in Biosciences and Biotechnology - ICABB-2018  (February 01-03, 2018) Organized by Department of Biotechnology, Jaypee Institute of Information Technology, Noida
  • Chetna Faujdar, Naveen Kumar Singh,Priyadarshini “Malondialdehyde content increases in Vero cell lines when exposed to calcium phosphate crystals” at 86th conference of “Society of Biological Chemists” (SBC), Emerging discoveries in health and agricultural sciences 16-19th Nov 2017, Jawaharlal Nehru University, New Delhi.
  • Priyadarshini,K. Jain, R. Sood. Rise of reactive oxygen species in renal cell line, injured by nano size calcium phosphate crystals. 49th Annual Conference of Urological Society of India (7-10 January 2016) organized by Hyderabad Urological Society, held at Hyderabad, India.
  • Priyadarshini,R. Agarwal, R. Sood. Anionic proteins purified from human calcium phosphate renal calculi decrease viability of injured epithelial cell line. 49th Annual Conference of Urological Society of India (7-10 January 2016) organized by Hyderabad Urological Society, held at Hyderabad, India.
  • Priyadarshini, K. Jain, R. Sood. Study of renal epithelial cell protein under stress condition. 1st International Conference on Novel Frontiers in Pharmaceutical & Health Sciences (INNOPHARM 1), (10-11 October 2015) organized by Innovare Academics Sciences at M.P. Council of Science & Technology, Vigyan Bhawan, Nehru Nagar, Bhopal MP, India.
  • A Kodesia, A Subramanian, S Kaul, T Raghav & Priyadarshini “Estimation of total flavanoid content and in-vitro antioxidant activity of some Indian medicinal plants” International Congress on “Agriculture, Food Engineering and Environmental Sciences- Sustainable Approaches” (AFEESSA- 2014) at Jawaharlal Nehru University, New Delhi, on 29th – 30th March, 2014.
  • Priyadarshini and A. Kodesia, “In-vitro antioxidant and anti-inflammatory activity of four Indian medicinal plants.” 83rd Annual meeting of the Society of Biological Chemists at KIIT University, Bhubneshwar on 18-21 December, 2014.
  • R. Agrawal, S. Jain, T. Vats andPriyadarshini. “Effect of Punica granatum and Glycine max on calcium phosphate mineralization”in InternationalJournal of Pharma and Biosciences, 2013, P020 (ISSN 0975-6299)
  • M. Makhijani, J. Chadha, R. Chawla, A. Jain and Priyadarshini “Management of osteoporosis through medicinal plants”. International Journal of Pharma and Biosciences., 2013, P025 (ISSN 0975-6299)
  • T. Vats andPriyadarshini. “Effect of calcium phosphate renal calculi extract on nucleation mineral phase” inJournal of proteins and proteomics, 2012 vol. 3, jpp47-48.
  • K. Aggarwal,P.Pathak, S. K. Singh, C. Tandon. “Bioactivity of lipids from human renal stone matrix in kidney stone disease,” inIndian Journal of Urology, 2012, suppl 1, vol 28, p-S50 [Indexed in Pubmed & SCOPUS Impact factor 1.46]
  • Priyadarshini,S.K. Singh, C. Tandon. “Studies on matrix protein(s) from human calcium oxalate monohydrate (COM) stones” (Abstract) inInternational Journal of Urology, 2010, 17: A212. [Indexed in PubMed & SCOPUS, Imfact factor 1.46].
  • K. Aggarwal .,Priyadarshini, S.K. Singh, C. Tandon. “Evaluation of the activity of human renal stone extract on nucleation and growth of calcium oxalate crystals” (Abstract) inInternational Journal of Urology2010; 17: A131-A132. [Indexed in PubMed & SCOPUS, Imfact factor 1.46]
  • A Aggarwal, S. K. Singla,Priyadarshini, C. Tandon, “In vitrostudies on anticalcifying potency of Tribulus terrestris”. (Abstract) inInternational Journal of Urology2010; 17: A211-A212. [Indexed in PubMed & SCOPUS, Imfact factor 1.46]
  • Priyadarshini,R. K. Bijarnia, T. Kaur, S. K. Singh, C. Tandon. “Comparison of the inhibitory activity of isolated lipids and proteins from calcium oxalate stones”. (Abstract)in 24 suppl.Indian Journal of Urology. 2008; 2: S111. [Indexed inPubMed & SCOPUS, Imfact factor 0.34]

WORKSHOP ORGANISED

  • Organised 3 days workshop on "Bioinformatics tools in Research" from 17th-20th September 2020 at Department of Biotechnology, Jaypee Institute of Information Technology, Noida.
  • Organised 2 Days workshop on “Ethical Issues in Research” on 27th-28th July 2019 at Department of Biotechnology, Jaypee Institute of Information Technology, Noida. 
  • Conducted workshop on “Molecular Biology” at Sanskar College of Pharmacy & Research on 24th April 2018

BOOK CHAPTER

  • Priyadarshini, Abhishek Negi “Anti-cancer Properties of Natural Compounds on Prostate Cancer” Anticancer plants: Properties and application edt by Akhtar & Swamy, Springer 2018, ISBN 978-981-10-8547-5
  • Chetna Faujdar & Priyadarshini "Natural Compounds Extracted from Medicinal Plants and Their Applications in Cardiovascular and Kidney Diseases" Natural Bio-active Compounds (Eds. M K Swamy, S Akhtar), Springer, 2018 (ISBN 978-981-13-7204-9)

 

  • ChetnaFaujdar; Priyadarshini, "Phytotherapy: A Safer Alternative of Available Medicines in the Management of Urolithiasis".Advances In Bioresources, Biodiversity And Therapeutics, (Eds. Prof.PammiGauba, Prof. Indira P Sarethy and Dr.AshwaniMathur) I.K. International Pvt. Ltd.2020, ISBN 978-93-86768-86-2
  • Shikha Mishra; ChetnaFaujdarPriyadarshini, "Biological Pathway and Diseases",Advances In Bioresources, Biodiversity And Therapeutics, (EdsProf.PammiGauba, Prof. Indira P Sarethy and Dr.AshwaniMathur). I.K. International Pvt. Ltd.2020 ISBN 978-93-86768-86-2
  • ChetnaFaujdar; Priyadarshini, "Role of Hyperoxaluria and Calcium Oxalate Crystals in Urolithiasis". Advances InBioresources, Biodiversity And Therapeutics, (EdsProf.PammiGauba, Prof. Indira P Sarethy and Dr.AshwaniMathur). I.K. International Pvt. Ltd. 2020 ISBN 978-93-86768-86-2

MEMBERSHIP OF PROFESSIONAL BODIES

  •  The Indian Science Congress Association (Membership No. A3598)
  •  Society of Biological Chemists (Membership No. 3084)
  •  Bioinformatics Organization

PhD Guidance

  • Completed- 01 (As CoPI)
  • Ongoing-03