Management (business school)

Despite noticeable improvements in combating the global burden of newly emerged, reemerged infectious and life-style diseases, millions of patients still fall prey to the unbridged gap in their understanding. Research at the Centre of Emerging Diseases focuses to delve into underlying molecular events behind pathogenesis of emerging viral and bacterial pathogens (host pathogen interactions, essential metabolic pathways of pathogens), along with life-style diseases such as cancer, cardiovascular diseases, etc. The faculty uses integrative structural biology approach to design novel diagnostics and therapeutics. The research activities at the Centre has generated ~ 7.5 crore extramural research funding from various agencies of Govt. of India including Department of Biotechnology (DBT), Department of Science & Technology (DST), Indian Council of Medical Research (ICMR) and All India Council for Technical Education (AICTE). Of the many interests of the faculty associated with the Center for Emerging Diseases, at the Department of Biotechnology, Jaypee Institute of Information Technology, Noida, major emphases are laid on the following topics: Newly emerged and re-emerged diseases in the recent past caused by SARS, Chikungunya (CHIKV)and other viruses have highlighted the vulnerability of developing and developed nations to such infectious diseases. Research efforts are on to understand the molecular and cell biology of pathogen-host-vector interactions in CHPV and CHIKV, pathogen specific remodeling processes of the host/vector cell, and to identify interactions which could be target for therapeutics and identify peptide-based inhibitors. In view of the rapid pace of emergence of multidrug resistant strains of almost all group of pathogens, the need for new antibacterial compounds cannot be overemphasized. Research efforts have been initiated to generate X-ray crystal structure(s) of potential drug targets from human pathogens, for early-stage rational drug discovery for a novel antimicrobial agent(s).