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Jaypee Institute of Information Technology, Noida
Associate Professor & Associate Dean (Policy Interfaces & Accreditation)
ashwani.mathur@jiit.ac.in
(+91)-120-2594 317

BIOGRAPHY

Dr. Ashwani Mathur has been working at Department of Biotechnology, JIIT since December 2010. Before joining JIIT, Dr. Ashwani Mathur worked for 18 months as Senior Lecturer at Department of Biotechnology and Bioinformatics at JUIT, Waknaghat, Dist. Solan, Himachal Pradesh. He has done his masters (M.Sc) in Biotechnology from Panjab University, Chandigarh in 2002, and was university rank holder. He completed his PhD from Department of Biochemical Engineering and Biotechnology, IIT Delhi in 2009. He had qualified CSIR JRF and GATE exams in 2002 and availed CSIR fellowship from MHRD during his PhD. He has also done post graduate diploma in business administration (PGDBA) from IMT Ghaziabad.

In past, Dr. Ashwani Mathur had worked as Scientist for Panacea Biotec Ltd., Delhi and Avesthagen Ltd., Bangalore. He has been associated with academia as a faculty for NSIT (formerly DIT, Delhi University), Dwarka and Manav Rachana International University (Formerly CITM), Faridabad. His core area of research includes process optimization for production of different primary and secondary metabolites. He has prior experience of handling microbial, algal, plant and mammalian cells in bioreactor.

RESEARCH HIGHLIGHTS

The research is focused toward exploring the role of bioprocess parameters in improving the yield of primary and secondary metabolites. We use various analytical and statistical tools to explore and optimize culture conditions for enhanced production of metabolites. Studies on optimization of culture conditions have been performed with various prokaryotic and eukaryotic systems including cellulose production from Acetobactor sp., saponin production from Bacopa monnieri.  Moreover, studies exploring the role of biopolymer based electrospun membranes as a suitable alternative to chemical membranes in Membrane Bioreactors (MBRs) have also been explored. Currently on-going studies are focused towards development of biosensors for environmental pollutants. Also, the optimization of hydroponic conditions for cultivation of medicinal plant Bacopamonnieri, are in progress.

PUBLICATIONS

  • A. Aggarwal, and A. Mathur. “Nexus between light and culture media on morphogenesis inBacopamonnieriand saponin yield thereof”. Heliyon, 2020; 6: e05245
  • C. Varshney , D.Gautam , A.Mathur. “Vanillin: A Wonder Molecule with Diverse Application and Alternative Manufacturing Strategies”. International Journal of Pharmacy and Pharmaceutical Research, 2020; 19(1): 933-939
  • P. Bhardwaj, N. Goswami, P. Narula, C.K. Jain, A. Mathur. “Zinc Oxide nanoparticles (ZnO NP) mediated regulation of bacoside biosynthesis and transcriptional correlation of HMG-CoA reductase genein suspension culture of Bacopa monnieri”. Plant Physiology and Biochemistry, 2018; 130. 148-156 [Indexed in Scopus and SCI; Impact Factor: 2.7].
  • P. Bhardwaj, C.K. Jain, A. Mathur. “Comparative evaluation of four triterpenoid glycoside saponins of Bacoside A in alleviating sub-cellular oxidative stress of N2a neuroblastoma cells ”, Journal of Pharmacy and Pharmacology, 2018. (DOI:10.1111/jphp.12993) [SCI & SCOPUS Indexed; Impact Factor: 2.309]
  • P. Bhardwaj, C.K. Jain, A. Mathur. “Comparative Analysis of Saponins, Flavonoids, Phenolics and Antioxidant Activities of Field Acclimatized and in-vitro Propagated Bacopa monnieri from different locations in India”. Indian Journal of Experimental Biology, 2018 (Manuscript accepted; Manuscript Number: IJEB EB 170427-1).
  • P. Bhardwaj, C.K. Jain, P. Mishra, A. Mathur. Comparative analysis of Bacoside-A yield in field acclimatized and in-vitro propagated Bacopa monnieri. International Journal of Pharmaceutical Sciences Review & Research, 44 (2); 168-175, 2017 [Indexed in SCOPUS]
  • P. Kapoor, and A. Mathur. Seabuckthorn juice: Nutritional therapeutic properties and economic consideration. International Journal of Pharmacognosy and Phytochemical Research, Vol. 9, pp. 880-884, 2017 [Indexed in SCOPUS]
  • P Sharma, G Mathur, S. Dhakate, S Chand, N Goswami, S K Sharma, A Mathur. “Evaluation of physicochemical and biological properties of chitosan / poly (vinyl alcohol) polymer blend membranes and their correlation for Vero cell growth”. Carbohydrate Polymers, Vol. 137, pp. 576-583, 2016.[indexed in SCOPUS, IF: 4.8]
  • R. Singh, A Mathur, N Goswami, G Mathur. Effect of carbon sources on physicochemical properties of bacterial cellulose produced from Gluconacetobacter xylinus MTCC 7795. e-Polymers, Vol. 16, pp. 331-336, 2016.
  • P. Bhardwaj,C.K. Jain, A. Mathur. Comparative Qualitative and Quantitative Analysis of Phytochemicals in Five Different Herbal Formulations of Bacopa monnieri, International Journal of Pharmacognosy and Phytochemical Research, 8 (4), pp. 675-682, 2016 [Indexed in SCOPUS ]
  • P Sharma, G Mathur, N Goswami, S. K. Sharma, S. R. Dhakate, S. Chand and A. Mathur. Evaluating the potential of chitosan/poly(vinyl alcohol) membranes as alternative carrier material for proliferation of Vero cells. e-Polymers, 15, pp. 237-243, 2015 [Indexed in SCOPUS, Impact factor: 0.33]
  • G. Mathur, A. Dua, A.R. Das, H. Kaur, S. Kukal, P. Sharma, N. Goswami, A. Sahai, A. Mathur. Bacterial cellulose: Biopolymer from Gluconacetobacter xylinus. Macromolecular Symposia, vol. 347, pp. 27-31, 2015 [Indexed in SCOPUS, Impact factor: 0.913].
  • Y. Bhatnagar, G.B. Singh, A. Mathur, S. Srivastava, S. Gupta and N. Gupta. Biodegradation of carbazole by Pseudomonas  sp. GBS.5 immobilized in polyvinyl alcohol beads. Journal of Biochemical Technology, vol. 6 (3), pp. 1003-1007, 2015.
  • R. Chhabra, A. Sachdeva, G. Mathur, P. Sharma, N. Goswami, C.K. Jain, S.K. Sharma, A. Mathur. Enhanced Production of Fungal Chitosan from Aspergillus niger Using Statistical Optimization. Journal of Chitin and Chitosan Science, Vol. 2, pp. 70-74, 2014.
  • R. Rana, A. Mathur, C.K. Jain, S.K. Sharma and G. Mathur. “Microbial production of vanillin.” International Journal of Biotechnology and Bioengineering Research, Vol. 4, pp. 227-234, 2013.
  • G. Mathur, N. Roy and A. Mathur. In vitro analysis of Aegle marmelos leaf extracts on skin pathogens. Journal of Applied Pharmaceutical Science, Vol. 3, pp. 97-100, 2013.
  • C.K. Jain, A. Gupta, A. Tewari, V. Sharma , V.S. Kumar, A. Mathur, S.K. Sharma. Molecular docking studies of bacoside from Bacopa monnieri with LRRK2 receptor. Biologia, Vol. 68, pp. 1068-1071, 2013 [Impact Factor: 0.5].
  • C.K. Jain, R. Sethi, V. Sharma, A. Mathur, S.K. Sharma. Enhanced Interaction of Shuffled Mutacin IV, an Antimicrobial Peptide of Bacterial Origin, with Surface Protein IsdB of Staphylococcus aureus. International Journal of Peptide Research and Therapeutics, Vol. 20, pp. 71-76, 2014.
  • S. Dhup, I. Thakur, G. Mathur and A. Mathur. An alternative substrate for laccase production from Pleurotus sp.  Journal of Bioprocess Technology, Vol. 98, pp. 233-239, 2013.
  • Gupta A, Sharma V, Tewari A K, Kumar V S, Wadhwa G, Mathur A, Sharma S K, Jain C K. “Comparative Molecular docking analysis of DNA Gyrase subunit A in Pseudomonas aeruginosa PAO1.” Bioinformation, Vol. 9, pp. 116-120, 2013.
  • M.S. Dayal, N. Goswami, A. Sahai, V. Jain, G. Mathur and A. Mathur. “Effect of media components on cell growth and bacterial cellulose production from Acetobacter aceti MTCC 2623.” Carbohydrate Polymer, vol. 94, pp. 12-16, 2013 [Indexed in SCOPUS, Impact Factor: 4.8].
  • R. Chhabra, A. Sachdeva, P. Sharma, G. Mathur and A. Mathur. “Bioprocess parameter optimization for improving yield of chitosan from Aspergillus sp.”, Asian Chitin Journal, vol. 9, pp. 8, 2013 (Abstract only).
  • G. Mathur, A. Mathur, B.M. Sharma and R.S. Chauhan. “Enhanced production of laccase from Coriolus sp. using Plackett Burman design.” Journal of Pharmacy Research, vol. 6, pp. 151-154, 2013.
  • M. Singh, G. Mathur, C.K. Jain and A. Mathur. “Phyto-pharmacological potential of Ginkgo biloba: a review.” Journal of Pharmacy Research, vol. 5, pp. 5028 -5030, 2012.
  • Mathurand S. Chand. Cloning and Expression of α-Amylase Gene in Escherichia coli: Effect on Specific Oxygen Uptake Rate and Host Cell Morphology during Batch Fermentation.  Indian Chemical Engineer, Vol. 53, pp. 111 – 123, 2012.
  • T. Anwar, A. Mathur, G. Mathur and R.S. Chauhan. Statistical optimization for co-production and partial characterization of thermo-halotolerant lipase and α-amylase from halotolerant Bacillus subtilis JPBW-9.  World Journal of Science and Technology, vol. 10, pp. 54-63, 2011.
  • G. Mathur, A. Mathur and R. Prasad. “Colonization and degradation of thermally oxidized High-Density Polyethylene by Aspergillus niger (ITCC no. 6052) isolated from plastic waste dumpsite.” Bioremediation Journal, vol.15, pp. 1-8, 2011.
  • G. Mathur, A. Mathur and R. Prasad. Isolation of Aspergillus fumigatus (ITCC no. 6050) from plastic waste dumpsite, with the ability to adhere and degrade High Density Polyethylene (HDPE) in submerged medium.  International Journal of Environmental Sciences and Engineering Research, vol.1, pp. 30-37, 2010.
  • Mathur, and S. Chand. “Model-based evaluation of plasmid segregational instability in repeated batch culture with recombinant Escherichia coli”. Chemical Engineering Journal, Vol. 15, pp. 227-230, 2009. (Indexed in SCOPUS; Impact Factor 2.816)

BOOK CHAPTERS

  • Mathur, P. Sharma, N. Goswami, A. Sahai, A. Dua, A.R. Das, H. Kaur, S. Kukal, M.S. Dayal,S. Arora, P. Mishra, V. Jain and G. Mathur. Comparative studies on production of bacterial cellulose from Acetobacter sp. and application as carrier for cell culturing. Industrial, Medical and Environmental Applications of Microorganisms: Current Status and Trends, Wageningen Academic Publishers, vol. 37, issue 8, pp. 403-407, 2014.
  • Mathur, R. Chhabra, A. Sachdeva, P. Sharma and G. Mathur. Fungal chitosan: a suitable biomaterial for cell culturing. Industrial, Medical and Environmental Applications of Microorganisms: Current Status and Trends, Wageningen Academic Publishers, vol. 37, issue 8, pp. 436-440, 2014.

PUBLICATIONS/PRESENTATIONS IN NATIONAL /INTERNATIONAL CONFERENCE PROCEEDINGS

  • P. Bhardwaj, C. K. Jain and A. Mathur. Abiotic parameters mediated transcriptional regulation of HMG-CoA reductase in in-vitro culture of Bacopa monnieri. Journal of Proteins and Proteomics, 2018, Vol. 9, pp. JPP 42.
  • S. Purswani, B. Lamba, S. Madan, S. Deb and A. Mathur. Evidence based validation of herbal medicines. Journal of Proteins and Proteomics, 2018, Vol. 9, pp.JPP 85
  • P. Bhardwaj, C.K. Jain, A. Mathur. Modulating cytoprotective potential of Bacopa monnieri extract by altering in-vitro culture condition. International Conference ‘Green for Good IV-G4G, 4th Meeting on Biotechnology of Plant Products, Czech Republic, June 19-22,2017, pp 35.
  • G. Mathur, P. Shukla, R. Chhabra, A. Sachdeva, A. Mathur. “Production and Isolation of Fungal Chitosan: Comparative Analysis of Physicochemical Properties”, in Proc. 56th Annual Conference of Association of Microbiologists of India (AMI-2015), 2015, pp. 636.
  • Aggarwal, G. Mathur, A. Mathur. “Endophyte Mediated Regulation of Saponin Production in In-Vitro Culture of Bacopa monnieri”,  in Proc. 56th Annual Conference of Association of Microbiologists of India (AMI-2015), 2015, pp. 709.
  • Raj, M. Sethi, A. Mathur, G. Mathur. Biotransformation of Eugenol to Vanillin By A Soil Isolate,in Proc. 56th Annual Conference of Association of Microbiologists of India (AMI-2015), 2015, pp. 733.
  • R. Singh, A. Mathur, G. Mathur. Bacterial Cellulose Production from Gluconacetobacter xylinus,in Proc. 56th Annual Conference of Association of Microbiologists of India (AMI-2015), 2015, pp. 808.
  • P. Sharma, G. Mathur, S.R. Dhakate, S.chand, N. Goswami, A. Mathur. Preparation of chitosan blended membranes: Effect of PVP blending on physiochemical and biological properties of CS membrane. International conference on Electron Microscopy and XXXV annual meeting of Electron microscope Society of India (EMSI), July 9-11, 2014, pp. 192.
  • P. Sharma, G. Mathur, S. R Dhakate, S. Chand, S. K. Sharma, N. Goswami, A. Mathur. Chitosan Reinforced Polyvinylpyrrolidone (PVP) Composite for Vero Cell Adhesion and Proliferation. 6th International Conference on Advancements in Polymeric Materials, February 20-22, 2015,pp. 298.
  • Mathur and K. Kaushik. A Philosophical and Bio-knowledge Based Reflection of Bioethics. National Seminar on Bioethics in Medical and Biological Research, In: International Journal of Pharmaceutical Sciences and Research (conference abstract only), February 14, 2014, pp. 1.
  • G. Mathur, A. Dua, A R Das, H. Kaur, S. Kukal, P. Sharma and A. Mathur. “ Production and characterization of bacterial cellulose from Gluconacetobacter xylinus”, in proc. 54th Annual Conference of Association of Microbiologist of India (AMI-2013), 2013,  pp. 322
  • R. Rana, A. Mathur, CK Jain, SK Sharma, G. Mathur. “Biotransformation of ferulic acid to vanillin by soil isolate”, in proc.54th Annual Conference of Association of Microbiologist of India (AMI-2013), 2013, pp. 384.
  • Dua, A R Das, H. Kaur, S. Kukal, P. Sharma, A. Mathur and G. Mathur. “Bacterial cellulose: biopolymer from Gluconacetobacter xylinus" in proc. International Conference on Science and Engineering of Materials, 2014.
  • Mathur, G. Mathur, M. S. Dayal, S. Arora, P. Mishra, V. Jain. “Comparative studies on production and characterization of bacterial cellulose from Acetobacter sp. and application as carrier for cell culturing”, inProc.Biomicroworld 2013 (V International Conference on Environmental, Industrial and Applied Microbiology, 2013, pp. 309.
  • G. Mathur, A. Mathur, R. Chhabra, A. Sachdeva and P. Sharma. “Fungal chitosan: a suitable biomaterial for cell culturing”, in Proc. Biomicroworld 2013 (V International Conference on Environmental, Industrial and Applied Microbiology, 2013, pp. 336.
  • S. Singh, H. Kaur, T Gupta, K. Jain, A. Mathur. “Microbial Production of Vanillin”, in Proc. International Conference on Bioproducts and Omics Revolution, 2013.
  • Patnaik, S. Gahlawat, A. Kalsi, S. Srivastava, A. Mathur. “Synbiotic Food: The Future Ahead”, in Proc. International Conference on Bioproducts and Omics Revolution, 2013.
  • Sachdeva, R. Chhabra, G. Mathur, P. Sharma and A. Mathur. “Production and Characterization of fungal chitosan extracted from soil fungal isolates”. in Proc. International Conference on Bioproducts and Omics Revolution, 2013. (Awarded Best Poster Award).
  • P. Sharma, G. Mathur and A. Mathur. “Biopolymeric Membranes for Membrane Bioreactor”. In Proc. International Conference on Bioproducts and Omics Revolution, 2013.
  • S. Arora, P. Mishra, G. Mathur, P. Sharma and A. Mathur. “Bioprocess parameter optimization for bacterial cellulose production”. In Proc. International Conference on Bioproducts and Omics Revolution, 2013.
  • Gupta, A. Tiwari, V. Sharma, V.S. Kumar, A. Mathur, S.K. Sharma, C.K. Jain. “Molecular docking studies of bacoside from Bacopa monnieri L. with LRRK2 receptor”. in Proc. International Conference on Industrial Biotechnology (ICIB-2012), 2012.
  • Mathur, S. Dhup, I. Thakur and G. Mathur. “Process parameter optimization for laccase production from soil fungal isolate and its purification using aqueous two phase separation,” in Proc. International Conference on Industrial Biotechnology (ICIB-2012), 2012.
  • R. Chhabra, A. Sachdeva, G. Mathur and A. Mathur. “Bioprocess parameter optimization for improving yield of chitosan from fungal isolates,” in Proc. International Conference on Industrial Biotechnology (ICIB-2012) 2012.
  • P. Poddar, G. Mathur, A. Dhiman and A. Mathur. “Process parameters optimization for biodegradation of High density polyethylene by Bacillus megaterium”, inProc. NHBT 2011, 2011, pp. 111.
  • G. Mathur, A. Mathur, B.M. Sharma and R.S. Chauhan. “Enhanced Production of Laccase from Coriolus sp. using Plackett-Burman Method.”, inProc. NHBT 2011,2011, pp. 105.
  • Kashyap, U. Bahal, N. Sejwal, R. Gabrani, A. Mathur and I.S. Sarethy “In-vitro propagation of the medicinal plant Solanum nigrum in liquid media and evaluation of its anti-oxidant property”. in Proc. NHBT 2011, 2011,pp. 230.
  • Gyanendu, G. Mathur and A. Mathur. “Statistical media optimization for improved α-amylase production by genetically identified soil fungal isolate in submerged fermentation,” in Proc. International Conference on Genomic Sciences, Nov. 12th-14th, 2010.
  • S. Sharma, H. Sood, A. Mathur, and R.S. Chauhan. “Optimization of Bioreactor Parameters for in-vitro production of medicinal compounds in shoot cultures of an endangered medicinal herb, Picrorhiza kurroa Royle ex Benth”. National Symposium on Plant Cell Tissue and Organ Culture: The Present Scenario. Centre for Advances Studies, Department of Botany, University of Calcutta, Kolkata, March 3-5, 2010.
  • V. Sharma, and A. Mathur. “Process Parameter Optimization for Phytase Production using Solid State Fermentation”. International conference on Biotechnology, Food and Bioengineering-Emerging Trends and Future Prospects. Centre for Research and Development, Prist University, Thanjavur, Tamilnadu. February 25-26, 2010. (Poster: 2nd Prize)
  • R.K. Baboota, V. Sharma, and A. Mathur. “Antimicrobial Peptides from pepsin hydrolyzed proteins of Kidney bean (Phaseolus vulgaris) & Mung bean (Phaseolus aureus)”. International conference on Biotechnology, Food and Bioengineering-Emerging Trends and Future Prospects. Centre for Research and Development, Prist University, Thanjavur, Tamilnadu. February 25-26, 2010.
  • V. Sharma, and A. Mathur. “Improved Phytase Production by Fungal Isolates using Solid State Fermentation”. National Seminar on Fungal Biotechnology, Mithibai College. Mumbai. January 7-9, 2010. (Oral Presentation: 2nd Prize).
  • Mathur and S. Chand. “Biochemical and genetic strategies for improving vector stability in recombinant E. coli.” The fifth of the Dhirubhai Ambani Life Sciences symposia series, International symposium on “Recent Advances in Biotherapeutics”, Reliance Institute of Life Sciences (RILS), Navi Mumbai (India). February 13-14, 2009.
  • G. Mathur and A. Mathur. “Technological Advancement in Mammalian Cell Culture,” in Proc. International symposium on Recent Advances in Biotherapeutics, Reliance Institute of Life Sciences (RILS), Navi Mumbai (India). February 13-14, 2009

CONFERENCES ORGANIZED

  • Co-organized International Conference “Bioproducts and Omics Revolution” jointly organized by Department of Biotechnology JIIT Noida and Scientity Inc. March 16-17, 2013.
  • Co-organized ASM “Virtual Workshop on Scientific Writing & Publishing” jointly organized by ASM, USA and Department of Biotechnology, JIIT Noida, Sep 28, 2012.
  • Co-organized International Conference “Bioproducts from Natural Sources”, jointly organized by Department of Biotechnology JIIT Noida and Scientity Inc. February 3, 2011

MEMBERSHIP OF PROFESSIONAL BODIES/ NATIONAL/ INTERNATIONAL COMMITTEES

  • Life member, Society of Biological Chemist of India.
  • Life Member, Association of Microbiologists of India.
  • Life Member, Biotech Research Society of India.

AWARDS/FELLOWSHIPS

  • Travel assistance from JIIT Noida for Oral Presentation in V International Conference on Environmental, Industrial and Applied Microbiology (BioMicroworld 2013, 2-4 October, 2013), Spain
  • Indian Institute of Chemical Engineers (IIChE) Awards 2012: Sisir Kumar Memorial for second best technical paper in ‘Indian Chemical Engineers’
  • IIChE NRC Award 2012 for second best Best Paper in ‘Indian Chemical Engineers’
  • Graduate Aptitude Test in Engineering (GATE) in LIFE SCIENCE(2002)
  • Qualified CSIR-UGC National Eligibility Test JRF in LIFE SCIENCE(2002)

CONTRIBUTION IN STUDENTS EXTRA & CO- CURRICULAR ACTIVITIES

  • Faculty Coordinator, RIBOSE (Technical Hub, Department of Biotechnology, JIIT Noida)
  • Member, Unnat Bharat Abhiyan (UBA) Cell, JIIT Noida

INVITED LECTURES DELIVERED

  • Delivered a  lecture on “Bioeconomic evaluation of Natural resources” (2017) during Faculty Development Program on ‘Bioentrepreneurship’  organized by Department of Biotechnology, Jaypee Institute of Information technology, Noida, U.P., from July, 10-15, 2017
  • Invited lecture on “A philosophical and bio-knowledge based reflection of Bioethics” (2014) in ICMR sponsored ‘National Seminar on Realization of Bioethics in Medical and Biological Research’, organized by Department of Zoology, Dev Samaj Post Graduate College for Women, Firozpur, Punjab on 14th February 2014.
  • Invited lecture on “Microbial Biomolecules: Carriers for Cell culture” at Institute of Biotechnology and Biomedicine, Universitat Autonoma de Barcelona, Barcelona, Spain on 3rd October 2013.
  • Delivered a lecture on “Industrial Enzyme & their Application” in National Science Seminar, organized by Department of Science, Dev Samaj College for Women, Ferozpur, Punjab on 15th December, 2012.

PATENT GRANTED

  • R.S. Chauhan, A. Anwar, A. Mathur, G. Mathur, A Malhotra.. Provisional patent filled for “Production of a Thermo-halotolarent Lipase by a New Strain of Staphylococcus arlettae”, (Patent Application No.1865/DEL/2010 A; Publication date: 15/03/2013).

Data submitted to open public access

(National Center for Biotechnology Information, USA)

  • T. Anwar, A. Mathur, and R.S. Chauhan, (2010), Staphylococcus arlettae strain JPBW-1, 16S ribosomal RNA gene, partial sequence, [Genbank Accession No HQ009504.1]
  • Mathur, R. Vanvari, P. Bhardwaj, G. Mathur, (2017), Brevibacillus panacihumi strain BMD16, 16S ribosomal RNA gene, partial sequence [Accession: MF350626]
  • Mathur, R. Vanvari, P. Bhardwaj, G. Mathur, (2017), Bacillus clausii strain BMH17, 16S ribosomal RNA gene, partial sequence [Accession: MF350627]