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Jaypee Institute of Information Technology, Noida
Professor
rachana@jiit.ac.in

Biography

Dr Rachana, Professor, Department of Biotechnology, Jaypee Institute of Information Technology has been working at JIIT since June 2009. She was working at SPTM, NMIMS University, Mumbai, before joining JIIT Noida. 

She post graduated in Biotechnology from IIT Roorkee in 1998 and achieved her doctorate from IIT Bombay in 2006. She has qualified NET-LS and GATE (Topper in Kanpur zone and 4th rank in India)in Life Sciences. She has been the recipient of DBT fellowship during her masters and JRF and research fellowship, from MHRD during her PhD. For her PhD she worked for designing a therapy for Adult Respiratory Distress Syndrome (ARDS). She has two Indian patents, two text books and have several international and national articles to her credit.

RESEARCH HIGHLIGHTS

She has been working to establish the mechanism of action of the herbal products in the field of diabetes, ashthma, respiratory infections, skin cancer, neurological disorders and COVID 19. Her group is also trying to work upon medicinal herbs for their preventive and therapeutic potential in case of tobacco smoke induced toxic conditions. The herbs which are majorly worked upon by the group are: SalaciaoblongaAdhatoda  vasica, Ginkgo biloba, Pirorhizakurroa, Punicagranatum, Musa paradisiacl, Citrus limetta,  Rose, Amaltas, Marigold, Jasmine, Kaner etc. Her goal is to establish the mechanism of action of the “Old Great Indian Herbal medicines so that they would be globally accepted. She has got grant from AYUSH, NMPB, Govt of India on Scientific Documentation and digitization for selected Indian medicinal plants for antidiabetic and other activities” in 2009.

Dr Rachana is a life time member of Indian Pharmaceutical Association, Biotechnology Society of India, Medicinal and Aromatic Plant Association of India and Mumbai Haematology Group. She remained the member of American College of Clinical Pharmacology (ACCP) for ~4 years. She was an Advisor on the South Asian Chapter of ACCP’s Student Outreach Committee (SOC) and IPA-SF Edufest.

Dr Rachana has been actively writing in scientific magazines such as CII, Ingredients of South Asia (international), Pharmabizz, Ingredient South Asia and Biospectrum.

AWARDS

  • First prize for poster presentation at Conference at MS baroda, 2000
  • First prize for Anti-TB campaign from team at SPTM, NMIMS, Mumbai, among the 50 Schools of pharmacy, across the country on 9 July, 2009, by IPA-SF congress-2009, at Bangalore.
  • Appreciated and awarded for excellence as a faculty, by School of Pharmacy and Technology Management, SVKM’s NMIMS University, Mumbai, 2009
  • IWAA Women Achievers Award by Anchor media for contribution in the field of education, 4th march, 2017
  • Golden global award for Health and Education for outstanding contribution in the field of Biotechnology, from Bellemie, at Islamic Cultural Centre New Delhi, India, 7 September 2019, IDMA approved

INTERNATIONAL PUBLICATIONS

  • S. Agarwal, V. Tyagi, M. Agarwal, A. Pant, H. Kaur, Rachana, M. Singh, “Controllable transdermal drug delivery of Theobroma cacao extract based polymeric hydrogel against dermal microbial and oxidative damage” Food and Nutrition Sciences, vol. 10:10, pp. 1212-1235, Oct 2019. ISSN Print: 2157-944X, Impact factor 0.97, (Web of Sc., JCR, Pubmed, Google Scholar)
  • Dipali. Verma, Sunita Gupta, R. Saxena, P. Kaur, Rachana R, S. Srivastava and V. Gupta, “Allosteric inhibition and kinetic characterization of KlebsiellapneumoniaeCysE: An emerging drug target”. International Journal of Biological macromolecules. Volume 151, 15May 2020, Pages 1240-1249 [Impact factor: 5.162] ISSN: 0141-8130 (Medline, Scopus, Elsevier, SCI/SJR)
  • Manisha Singh, Surinder P. Singh, P.K. Dubey, Rachana R, Shalini Mani, Deepshikha Yadav, Mugdha Agarwal, Shriya Agarwal, Vinayak Agarwal and Harleen Kaur, “Advent of Proteomic Tools forDiagnostic Biomarker Analysis in Alzheimer’s Disease”, Current Protein and Peptide Science, 15 June, 2020, Vol. 21, No. 00 pp1-13 (Bentham Science) ISSN: 1875-5550 (Online), (Web of science, Scopus, Google Scholar, Scimago) Impact 2.5.
  • Ayushi Bhagat and Rachana, “Bromhexine: a comprehensive review”. International journal of Biological and Medical Research, 9, 3, pp6455-6459, 2018.
  • Rachana, M. Singh and T. Gupta, “Topical Application of Melaleuca Alternifolia for Skin Cancer and Other Conditions” Cancer therapy & Oncology International Journal, 8, 2, pp01-04,  December, 2017.
  • M. Singh, R. Kaur, S. P Singh and Rachana,Intranasal Drug Delivery- New Concept of Therapeutic Implications for Effective Treatment of CNS Disorders”,International Journal of Pharmaceutical Sciences, 8,8, pp1000-1013, Jan 2017.
  • M. Singh, S. P. Singh and R. Rachana, “Development, Characterization and Cytotoxicity Evaluation of Gingko biloba extract (EGB761) loaded Microemulsion for Intranasal Application”, Journal of Applied Pharmaceutical Science, 7, 1, pp024-034, Jan 2017.
  • R Kaur, R. Rajput, P. Nag, S.Kumar, Rachana, M. Singh, “Synthesis, characterization and evaluation of antioxidant properties of catechin hydrate nanoparticles” Journal of Drug Delivery Science and Technology 39 pp398- 407, June 2017.
  • M. Singh, S. P. Singh and Rachana R., “Antioxidant, Cytotoxicity, and Stability of Ginkgo bioloba extract-based Microemulsions for enhanced Therapeutic Activity”, Asian J Pharm Clin Res, Vol10, 8, pp1-6, April 2017.
  • Rachana*, Kritika Sehgal and Manisha Singh, “ Essentials to kill the cancer”,Canc Therapy & Oncol Int J., 4, 5, pp01-04, May 02, 2017.
  • Rachana, Manisha S, Tanya G. Topical Application of Melaleuca alternifolia for Skin Cancer and Other Conditions. Canc Therapy & Oncol Int J., 8, 2, pp001-004, December 05, 2017
  • R. Kaur, M. Singh and Rachana, “Exploring the therapeutic neuropepetides in neurodegenerative diseases (NDD): A review”, International Journal of Research in Engineering and Applied Sciences (IJREAS) 6,11, pp189-200Nov 2016.
  • Rachana, M. Pant, S. Basu, A. Jain, N. Goel I wadi, “A review on herbal therapy for respiratory ailments”, International Journal of Life Sciences and PharmaRresearch, vol 6, 2, pp11 -15, 2016
  • M. Pant, S. Basu , R. K. Sindhu and Rachana, “Antioxidant and free radical scavenging potential of ethanolic fraction of Adhatoda vasica in A549 cell line”, Asian Journal of Pharamceutical and Clinical Research, 8, 6, pp244-249, 2015.
  • M. Pant, S. Basu and Rachana, “Cytotoxic Effects of Indian Tobacco Rolls (Bidi) Smoke Extract on Macrophages & its Prevention by Alkaloid Vasicine Obtained by Adhatoda vasica”, Indo Global Journal of Pharmaceutical Sciences, vol 5, 2, pp99-105, 2015.
  • S. Basu, M. Pant, and Rachana, “Protective effect of Salacia oblonga against tobacco smoke-induced DNA damage and cellular changes in pancreatic β-cells” Pharmaceutical Biology, Early Online: pp 1-7, 2015.
  • S. Thakur and Rachana, “Diabetic Neuropathy: Its Pathogenesis and Therapeutic Drug Targets” Journal of Cell Science and Molecular Biology, vol 1,1, pp 1-6, 2014.
  • S. Basu, M. Pant and Rachana, “Phytochemical evaluation and HPTLC profiling of extracts of Salacia oblonga” International Journal of Pharmaceutical Sciences and Research, vol. 4, 4, pp 1409-1418, 2013.
  • S. Basu, M. Pant and Rachana, “In vitro antioxidant activity of methanolic-aqueous extract powder (root and stem) of Salacia oblonga” IJPPS, vol. 5, 3, pp 904-909, 2013.
  • M. Pant, S. Basu and Rachana, “Toxic effects of Indian tobacco rolls (Bidi) and beneficial role of vasicine on mitochondrial localization and antioxidant enzymes activity in A549 cell line”, International Journal of Biotechnology and Bioengineering Research, 4, 5, pp 273-280, November 2013.
  • S. Basu, M. Pant, and Rachana, “Beneficial effects of Salacia oblonga on mitochondrial localization in cells and NADPH oxidase activity in glucose induced cytotoxicity on rat muscle cell line”, International Journal of Biotechnology and Bioengineering Research, 4, 4, pp321-328, November 2013.
  • S. Agrawal, P. Sharma, N. Chaoudhary, S. Agarwal, and Rachana, “Ovarian cancer and its diagnosis using Quantum Dots”, The Pharma Review, vol. 11, 61, pp88-92, Jan-Feb. 2013.
  • M. Pant, S. Basu, and Rachana, “Anti-oxidant activity and cytoprotective potential of ethanolic extract of Adhatoda vasica”, International Journal of PharmTech Research, 5, 2, pp 501-510, 2013.
  • S. Gupta and Rachana, “Respiratory Distress Syndrome and Surfactant Therapy”, The Pharma Review, 10, 46, pp64-67, Mar –Apr. 2012.
  • S. Gaur, P. Gauba, S. K. Maheshwari and Rachana, "Transgenic plant production technology: Present and Future Prospective", The Pharma Review, 10, 55, pp89-94, Jan-Feb. 2012.
  • Rachana, S. Basu, M. Pant, M. P. Kumar, S. Saluja, “Review and future perspectives of using Vasicine, and related compounds” Indo Global Journal of Pharmaceutical Sciences, 1, pp85-98, 2011.
  • P. M. Kumar, S. Saluja, Pant M., Rachana and C. Jain. “Docking studies to investigate interactions of vasicine molecule with oxidative enzymes”, Journal of Pharmacy Research, 4, 11, pp3907-3909, 2011.
  • S. Basu and Rachana, “IPR issues with Genetically Modified Organisms (GMOs)”, The Pharma Review, 8, 44, pp 64- 67, March 2010.
  • S. Shah and Rachana, “Development and optimization of an economic method for quantitation of azithromycin in human plasma by tandem mass spectroscopy ((LCMS/MS) for clinical trials, Pharma Science Monitor, pp 1-13, 2010.
  • Rachana and R. Banerjee, "Effects of albumin and erythrocyte membranes on spread monolayers of lung surfactant lipids", Colloids and Surfaces B, 50, pp 9-17, 2006.
  • Rachana and R. Banerjee, "Interaction between hematological derivatives and dipalmitoylphosphatidylcholine: implication in Adult Respiratory Distress Syndrome", Colloids and Surfaces B, vol. 34, pp 95-104, 2004.

International conferences attended and conference publications - 58

NATIONAL PUBLICATIONS

  • Rachana, M. Pant, S. Basu, A Jain, N. Goel and I. Wadi, “Using Indian medicinal herbs to deal with oxidative stress” Abstract book for IX the national conference Current trends and Future challenges in Environmental Science, Biotechnology, AYUSH and Biomedicine for Human welfare and Sustainable development, Organized by Department of Botany and Biotechnology, Govt New Science College, Rewa, M.P. pp 23-24, April, 2014. (Abstract)
  • Rachana and G. Pathak, “The Potential of white biotechnology for present and future”, Pharma Times, vol. 41, 5, pp. 9-13, May 2009
  • Rachana, "Surfactant Therapy" Biospectrum, India, pp 88-89, September, 2008
  • R. S. Gaud and Rachana, "Pharmacogenomics for smaller, safer, better drugs", CIIM, pp 48-50, September, 2008
  • Rachana and R.Banerjee, “Relative susceptibility of lung surfactant lipids for haematological inhibition”, Indian Journal of Physiology and Pharmacology, vol. 48, 5, supplement, pp 213, 2004

PATENTS

  • R. Banerjee, Rachana, J. Bellare and R. R. Puniyani, “For the formulation developed to treat NRDS.” Indian Patent 241271 (1222/MUM/2005) 29 June 2007
  • R. Banerjee, Rachana, J. Bellare and R. R. Puniyani, “For the formulation developed to treat ARDS.” Indian Patent 2412712 (1223/MUM/2005) 29 June 2007

PROJECT GRANTS

  • Project from NMPB, Ayush: Scientific documentation (digitization) of selected Indian medicinal plants (Salacia reticulata and Andrographis paniculata) used for anti-diabetic activity, October, 2008-2011

BOOK CHAPTERS

  • Rachana, S. Thakur, S. Basu, “Oxidative stress and Diabetes” in “Free Radicals in Human Health & Diseases”, Editors: Vibha Rani Umesh Chand Singh Yadav, Springer publication, pg 241-257, 2014
  • Ramneek Kaur, Rashi Rajput, Sachin Kumar, Harleen Kaur Rachana and Manisha Singh, “Designing of Natural Anticancerous Drugs and Their Delivery System Anticancer Plants: Clinical Trials and Nanotechnology”, Volume 3, chapter 5, pg163-180, 2017.
  • Manisha Singh, Rashi Rajput, Ramneek Kaur, Sachin Kumar, and Rachana, “Designing of Natural Anticancerous Drugs and Their Delivery System” in “Anticancer Plants: Clinical Trials and Nanotechnology,Editors: M. S. Akhtar, M. K. Swamy, Springer Nature Singapore Pte Ltd., Volume 3, Chapter - 5, pg 163-180, 2017.
  • Manisha Singh, Rashi Rajput, Ramneek Kaur, Sachin Kumar, and Rachana, “Pharmacotherapy of Cognitive Deficits in, Advances in Neuropharmacology Drugs and Therapeutics, Apple Academic Press in 2018.
  • Ramneek Kaur, Rashi Rajput, Sachin Kumar, Harleen Kaur, Rachana and Manisha. Singh, “Pharmacotherapy of Cognitive Deficits”, in“Advances in Neuropharmacology Drugs and Therapeutics”, Editor: Md. Sahabuddin, Apple Academic Press, Chapter - 11, pg 172-187, 2018.
  • Rashi Rajput, Ramneek Kaur, Rishika Chaddha, Shalini Mani, Rachana, Harleen Kaur and Manisha Singh, “The Aging Brain: From Physiology to Neurodegeneration”, Chapter – 1, pp1-23, Handbook of Research on Critical Examinations of Neurodegenerative Disorders, Editor: Md. Sahabuddin, Apple Academic Press, Chapter – 1, pg 1-23, 2018.
  • Rachana, Tanya Gupta, Saumya Yadav and Manisha Singh Therapeutic Gases: Oxygen, Carbon Dioxide, Nitrogen and Helium” in Advances in Neuropharmacology: Drugs and Therapeutics. Apple Academic  press
  • Rachana, Tanya Gupta, Saumya Yadav and Manisha Singh Opioids Analgesics and Antagonists” has been accepted provisionally for the upcoming book entitled “Advances in Neuropharmacology: Drugs and Therapeutics” Advances in Neuropharmacology Drugs and Therapeutics, Apple Academic Press 
  • Ramneek Kaur, Rashi Rajput, Sachin Kumar, Harleenkaur,Rachanaand Manisha Singh, “Cognition enhancers” Apple Academic Press and CRC Press (Tayler and Francis) January 2020, pp447-466. ISBN: 13:978-1-77188-797-7
  • SujataBasu, Manisha Singh, Mansiverma, and Rachana“BCL-2 Associated Anthanogene 3 (BAG3) protein in Neurodegenration and its therapeutics” Quality control of cellular protein in Neurodegenration disorders, IGI Global eEditorial Discovery, 261-281, ISSN:2475-6628, 2020
  • MansiVerma, SujataBasu, and Rachana“Role of alpha synculin in Parkinsons Disease and its therapeutics”Quality control of cellular protein un Neurodegenration disorders,pp 212-234, IGI Global eEditorial Discovery ISSN:2475-6628, 2020
  • Sakshi Singh Manisha Singh and Rachana*, Role of environmental pollution causing Multiple Sclerosis and advances in therapeutics in Advances in Bio resources, Biodiversity and Therapeutics, pp 229-254, I.K. International Pvt. Ltd. New Delhi, 2020
  • Shriya Agarwal, Prakhar Agarwal, Mugdha Agarwal, Rachana, Manisha Singh, “Alkaloids as Central Nervous System Stimulants” CHAPTER18 in in Advances in Bio resources, Biodiversity and Therapeutics, pp 229-254, I.K. International Pvt. Ltd. New Delhi, 2020pp208-228
  • Mansi Sharma and Rachana, “Transdermal therapeutics for the treatment of cancer” Submitted in Advances in Biotechnology and Life Sciences, VidyaKutir Publications.
  • Manisha Singh, Pranav Pancham, Shriya Agarwal, Harleen Kaur, Vinayak Agarwal, Raj Kumar Tiwari, Shalini Mani, Rachana “Role of Immunotherapy in Ameliorating Proteins Accumulation Associated with Dementia” in Dementia Research: From Risk Factors to Therapeutic Interventions

TEXT BOOKS AND MONOGRAPHS

  • Rachana and S. Basu, Biochemistry (for BSc), Punjab Technical University, Vikas publications, Noida, India, 2011
  • Rachana, S. Sharma and Basu, S. Human physiology and anatomy (for MSc), Punjab Technical University, Vikas publications, Noida, India, 2011
  • Rachana, S. BasuBasics of Zoology, (for BSc.), Manonmaniam Sundaranar UniversityTirunelveli, Vikas publications, Noida, India, (Accepted)
  • Mono Graphs submitted: to AYUSH, NMPB, Ministry of Health, Govt. of India
  • Monograph for the Indian medicinal plant Salacia reticulata
  • Monograph for the Indian medicinal Andrographis panicualta

INVITED TALKS

  • International Webinar onNew Advent of Ancient Herbs for ImmunomdulationVirucidal ActivityConducted by Enliven Archive on 22nd July 2020
  • International Webinar on “Antiviral herbs: rediscovered” organised by Enliven Archive on 12 June, 2020
  • Panelist, FAN IIT Bombay Symposium on New and Advanced materials and Sustainable Sciences, at, Goa, on 6th April 2019 by IIT Bombay
  • Keynote speakerat April 27-28, 2020 at Pharmacology & Drug Development Congress (SciTech Central Pharma 2020) at Palms Hotel, Mauritius.: Nano therapeutics for plant based natural products for respiratory disorders”
  • Keynote Speakerand Co-chair, “Phytocompound based Nano medicine approaches for the rescue of neural disorders”, Rachana, Manisha Singh and Surya Pratap Singh, at 2nd Global Conference on Plant Science and Microbial Ecology, 14-15 October, 2019, at Hotel Crowne Plaza, Dubai by Scient global Conferences and Editors of Journal of Integrative Plant Science and Molecular Biology. 
  • Key Note Speaker on “Phytocompound based Nano medicine approaches for the rescue of neural disorders”, Rachana, Manisha Singh and Surya Pratap Singh, at 2nd Global Conference on Plant Science and Microbial Ecology, 14-15 October, 2019, at Hotel Crowne Plaza, Dubai by Scient global Conferences and Editors of Journal of Integrative plant Science and Molecular Biology.
  • Natural Products and Cancer Therapeutics” ICN:3I-2017, 06-08 Dec 2017, IIT Roorkee organised by Department of Mechanical and Industrial engineering and Centre of Nan technology, IIT Roorkee.
  • Anticancer activity of religiously important plants from India “Cancer Diagnostics 2016” at Rome. 13th to 15th June, 2016, Organized by Omics International.
  • Natural products as anticancer agents, Journal of Cancer Science and Therapy, 7, 10, 2015, pp 77, 9th Indoglobal summit on cancer therapy, 2-4 November, 2015, Hyderabad, Organized by Omics International.
  • Anticancer activity of religiously important plants from India” “Cancer Diagnostics 2016” at Rome. 13th to 15th June, 2016, Organized by Omics International.
  • Natural products for diabetes, International Conference on Life Sciences and Bioengineering 2014”, organized by Department of Life Sciences, IAMR, Ghaziabad on 22-23 November, 2014.
  • Using Indian medicinal herbs to deal with oxidative stress XI National conference on Current trends and Future challenges in Environmental Science, Biotechnology, AYUSH and Biomedicine for Human welfare and Sustainable development, Organized by Department of Botany and Biotechnology, Govt New Science College, Rewa, M.P., 26-27 April 2014.
  • Use of Indian medicinal plants for respiratory diseases at Future Prospects of Advancements in Biological Sciences, Health Issues and Environmental Protection Future Prospects of Advancements in Biological Sciences, Health Issues & Environmental Protection” on 07–08 Feb 2014, at Lucknow, Sponsored by Council of Science & Technology, Govt. of Uttar Pradesh, organized by CytoGene Research & Development, Lucknow and Society of Biosciences, Health issue and Environmental protection [SBHE], Lucknow.
  • Surfactant Therapy for ARDS Oral Invited presentation at International Conference “Recent Developments, Future Prospects and Entrepreneurial Trends in Biotechnology”, IET Biotechnology Institute, Alwar, Rajasthan, December, 2009.

Membership

  • IIT Bombay Alumni Association
  • Biotechnology Society of India (ID 524/ L363)
  • Medicinal and Aromatic Plant Association of India
  • Indian Pharmaceutical Association, Life time membership (MH/LM/1302)
  • American College of Clinical Pharmacology (2782) 2008-2011
  • Worked as Advisor on the South Asian Chapter of ACCP’s Student Outreach Committee (SOC,2009 )
  • Worked as Advisor for IPA-SF edufest (2009)
  • Member of advisory board: GBIOFIN
  • Member of Advisory committee FAB-HEP 2014 (International conference)

Editorial member

Reviewer

  • International Journal - African Health Sciences
  • BMC Complementary & Alternative Medicine

Members of steering committees of international conferences recognized by reputed organizations

  • Advisory committee of International conference, Future Prospects of Advancements in Biological Sciences, Health Issues & Environmental Protection” (FAB-HEP) on 07–08 Feb 2014, at Lucknow, Sponsored by Council of Science & Technology, Govt. of Uttar Pradesh, organized by CytoGene Research & Development, Lucknow and Society of Biosciences, Health issue and Environmental protection [SBHE], Lucknow
  • Organizing secretary, International Conference of Life Sciences, Informatics, Food and Environment, 29-30 August 2014, Organized by Department of Biotechnology, JIIT Noida
  • Member of Board of studies and Academic council, JIIT Noida, 2011-2014
  • IAQAC member for professional and social activities at JIIT Noida 2014-15
  • Member of Board of studies JIIT Noida 2016-2017
  • Member of Department Quality Assurance Cell 2020-21

PhD Completed : 3+ 2 Continuing